Dr. Rakesh K. Srivastava
Dr. Rakesh K. Srivastava is an accomplished entrepreneur and is the CEO and President of GLAX Health LLC.
WILMINGTON, DELAWARE, UNITED STATES, August 30, 2022
— Dr. Rakesh K. Srivastava’s Research on Plant Polyphenols and their Role in Preventing Cancer
It has been suggested that chemoprevention is an effective strategy for preventing cancer in high-risk individuals. Plant polyphenols (PPs) are one class of chemopreventive medicines that are both safe and effective in bioassays and animal models for blocking carcinogen-induced mutagenesis and carcinogenesis at a variety of target organ sites. Oncologists have a strong interest in plant-based substances. Dr. Srivastava recommends Genistein (found in soy), apigenin (celery, parsley), luteolin (broccoli), quercetin (onions), kaempferol (broccoli, grapefruits), curcumin (turmeric), etc., due to their chemopreventive and chemotherapeutic potential against human cancer. Stick around to learn more about Plant Polyphenols and Dr. Rakesh K. Srivastava’s research on its role in preventing cancer.
Plant polyphenols (PPs) have emerged as both major prospective chemopreventive agents and therapeutic and natural antioxidants, thanks to the growing interest in cancer chemoprevention through diet. Chemotherapy is referred to as chemoprevention when used to treat precancerous lesions, also known as preinvasive neoplasia, dysplasia, or intraepithelial neoplasia. There is a common misunderstanding concerning chemoprevention that centers on the hope of eliminating cancer. Since carcinogenesis is the method by which cancers arise, Dr. Srivastava believes that the main focus should be to lower cancer burden.
Therefore, he considers chemoprevention to be the achievable aim of reducing carcinogenesis. Although PPs have been shown to affect various nodes in intracellular signal transduction pathways involved in cell proliferation, differentiation, apoptosis, inflammation, angiogenesis, and metastasis, their molecular mechanisms of action have yet to be fully characterized, and many features remain to be elucidated. Green tea polyphenols and soy polyphenols, particularly, have garnered much attention due to their documented chemopreventive effects against multiple human malignancies. Reduced cell transformation and proliferation, or increased cell cycle arrest and death, may account for PPs' chemopreventive actions. Several human cancer cell lines, including those for leukemia, melanoma, breast, pancreatic, prostate, brain, lung, and colon cancers, have been demonstrated to be sensitive to polyphenols' growth-inhibiting and apoptosis-inducing effects in vitro.
A lot of research has been done in vitro to determine how PPs might produce these results. The chemopreventive effects of PPs have also been found in vivo in selected animal models, albeit the underlying mechanism(s) remain unclear.
Secondary products, as they are often known, can be powerful bio-antimutagens. Researchers have looked into the anticancer effects of PPs and found that many substances appear to be responsible. Due to their potential benefits to human health and nutrition, researchers are keen to learn more about natural chemicals that act as free radical scavengers. By lowering free radical generation and oxidative stress, protecting low-density lipoprotein (LDL) oxidation and platelet aggregation, and preventing the creation of proinflammatory cytokines, dietary polyphenols may help reduce cancer disease. In this article, Dr. Srivastava discusses the PPs that are effective against different types of cancer, emphasizing the fundamental ideas behind phenolics that have powerful antioxidant activity so that the reader can form their own opinions about which PPs they think are most promising.
The public and scientific communities have paid close attention to the cancer-fighting properties of fruits, vegetables, and spices for quite some time. The method by which these dietary supplements inhibit cancer, and the specific component of these agents responsible for their anticancer actions, have attracted the attention of medical researchers. Many of the dietary agents that have been employed for thousands of years in traditional medicine are plant-based, physiologically active substances.
In addition to polyphenols, the fiber, vitamins, minerals, terpenes, and alkaloids found in fruits and vegetables may contribute significantly to one's health. Several of the micronutrients found in fruits and vegetables have been demonstrated to inhibit cancer growth in studies conducted over the past decade.
Dr. Rakesh Srivastava has spent his entire career working to improve the state of medical knowledge regarding cancer. We hope you've thoroughly understood the role of plant polyphenols in preventing cancer. Dieting is only a temporary fix, so it's best to focus on seeking a qualified health practitioner.
Contact: Dr. Rakesh Srivastava
www.rksrivastava.com
Email: contact@glaxhealth.com
Rakesh Srivastava
GLAX, LLC.
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